Abstract
Vaccines can have adverse side-effects, and these are predominantly associated with the inclusion of chemical additives such as aluminum hydroxide adjuvant. The objective of this study was to establish an in vitro model system amenable to mechanistic investigations of cytotoxicity induced by hepatitis B vaccine, and to investigate the mechanisms of vaccine-induced cell death.

http://www.ncbi.nlm.nih.gov/pubmed/?term=hepatitis+b+vaccine+apoptosis+hamza